Born in 1953 into a family of producers of Brunello di Montalcino, Donatella graduated in History of Medieval Art. In 1993 she founded the “Wine tourism movement” and invented Wine Day, the event that in a very short time brought success to Italian wine tourism.
Today she teaches in master courses in three universities. In 1998, after 14 years in the family estate, she created her own, made up of Fattoria del Colle in Trequanda – with a country inn a restaurant and the production of the Chianti and Doc Orcia wines wine – and Casato Prime Donne in Montalcino. This is where the Brunello is made, in a winery among the first in Italy to be staffed only by women. In 2003 Donatella won the "Oscar" for Best Italian wine producer, a prize awarded by the Italian Association of Sommelier-Bibenda, and she published the Manuale del turismo del vino (a handbook for producers on how to organize, and successfully open their wineries to the public). From 2001 to 2011 she worked as tourist advisor for the city of Siena. In 2007 Donatella Cinelli Colombini publishes Marketing del turismo del vino (a handbook on the marketing for wine tourism). Among her projects is "Urban trekking," a new type of sports tourism, which from Siena has been exported to 34 other cities in Italy. Donatella Cinelli Colombini since 2008 is Vice President of the Enoteca Italiana and since 2013 Vice President of Donne del Vino ( Women in wine ). In may 2013 she became President of Consorzio del vino Orcia.