Montepulciano is known as the "pearl of the 16th century" : this is because of its abundance of Renaissance buildings designed by famous architects: Michelozzo, Antonio da Sangallo, Baldassare Peruzzi, Vignola. One can admire these as one walks through the main square. Just out of the village stands the "Tempio di San Biagio" by Antonio Sangallo (1518-1545) a solemn and harmonious building in travertine. The building is shaped like a Greek cross and culminates with a tall dome, the facades are made up of pillars, frames and balustrades. On the inside, which is very bare, once can appreciate the acoustics (try and clap your hands when in the centre of the building).